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В.И. Польшаков

Аватар пользователя В.И. Польшаков
Владимир
Иванович
Польшаков
Место работы, город: 
МГУ имени М.В.Ломоносова, Москва
Степень: 
д.х.н.
Должность, звание: 
в.н.с.
Публикации: 
  1. A.A. Kulikova, P.O. Tsvetkov, M.I. Indeykina, I. Popov, S.S. Zhokhov, A.V. Golovin, V.I. Polshakov, E. Nudler, S. Kozin, A.A. Makarov (2014) Phosphorylation of Ser8 promotes zinc-induced dimerization of amyloid-β metal-binding domain, Molecular BioSystems, 10, 2590-2596.
  2. K.V. Kudryavtsev, C.-C. Yu, P.M. Ivantcova, V.I. Polshakov, A.V. Churakov, S. Bräse, N.S. Zefirov, J.-H. Guh (2015) Structural studies and anticancer activity of a novel class of β-peptides, Chemistry – An Asian Journal. 10(2): 383-389, DOI: 10.1002/asia.201403171.
  3. E. Smirnova, I. Safenkova, V. Stein-Margolina, V. Shubin, V. Polshakov, B. Gurvits (2015) pH-responsive modulation of insulin aggregation and structural transformation of the aggregates, Biochimie, 109(2): 49-59. DOI: 10.1016/j.biochi.2014.12.006.
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    S.A. Kozin, A.A. Kulikova, A.N. Istrate, P.O. Tsvetkov, S.S. Zhokhov, Y.V. Mezentsev, A.S. Ivanov, V. I. Polshakov, A.A. Makarov (2015) The English (H6R) familial Alzheimer’s disease mutation facilitates zinc-induced dimerization of the amyloid-β metal-binding domain, Metallomics, 7: 422-425. DOI: 10.1039/C4MT00259H.

  5. N. Logunova, M. Korotetskaya, V. Polshakov, A. Apt (2015) The QTL within the H2 Complex Involved in the Control of Tuberculosis Infection in Mice Is the Classical Class II H2-Ab1 Gene, PLoS Genetics 11(11): e1005672, 1-22. DOI:10.1371/journal.pgen.1005672.
  6. A.N. Istrate, S.A. Kozin, S.S. Zhokhov, A.B. Mantsyzov, O.I. Kechko, A. Pastore, A.A. Makarov,  V.I. Polshakov (2016) Interplay of histidine residues of the Alzheimer's disease Aβ peptide governs its Zn-induced oligomerization. Scientific Reports, 6: 21734; doi: 10.1038/srep21734.
  7. A.N. Tevyashova, A.M. Korolev, A.S. Trenin, L.G. Dezhenkova, A.A. Shtil, V.I. Polshakov, O.Yu. Savelyev, E.N. Olsufyeva (2016) New conjugates of polyene macrolide amphotericin B with benzoxaboroles: synthesis and properties. Journal of Antibiotics, 69: 549-560. doi:10.1038/ja.2016.34.
  8. K.V. Kudryavtsev, A.B. Mantsyzov, P.M. Ivantcova, M.N. Sokolov, A.V. Churakov, S. Brase, N.S. Zefirov, V.I. Polshakov (2016) Control of Azomethine Cycloaddition Stereochemistry by CF3 Group: Structural Diversity of Fluorinated β-Proline Dimers. Organic Letters, 18: 4698-4701. DOI: 10.1021/acs.orglett.6b02327.
  9. A. Shebanova, T. Ismagulova, A. Solovchenko, O. Baulina, E. Lobakova, A. Ivanova, A. Moiseenko, K. Shaitan, V. Polshakov, L. Nedbal, O. Gorelova (2017) Versatility of the green microalga cell vacuole function as revealed by analytical transmission electron microscopy. Protoplasma, 254: 1323-1340.
  10. V.I. Polshakov, A.B. Mantsyzov, S.A. Kozin, A.A. Adzhubei, S.S. Zhokhov, W. van Beek, A.A. Kulikova, M.I. Indeykina, V.A. Mitkevich, A.A. Makarov (2017) A binuclear zinc interaction fold discovered in homodimer of Alzheimer’s amyloid-β fragment with Taiwanese mutation D7H. Angewandte Chemie International Edition, 56(39): 11734-11739.
  11. O.A. Petrova, A.B. Mantsyzov, E.V. Rodina, S.V. Efimov, C. Hackenberg, J. Hakanpaa, V.V. Klochkov, A.A. Lebedev, A.A. Chugunova, A.N. Malyavko, T.S. Zatsepin, A.V. Mishin, M.I. Zvereva, V.S. Lamzin, O.A. Dontsova, V.I. Polshakov (2018) Structure and function of the N-terminal domain of the yeast telomerase reverse transcriptase. Nucleic Acids Research, 46(3): 1525–1540, DOI: 10.1093/nar/gkx1275.
  12. A.B. Mantsyzov, O.Y. Savelyev, P.M. Ivantcova, S. Brase, K.V. Kudryavtsev, V.I. Polshakov (2018) Theoretical and NMR conformational studies of β-proline oligopeptides with alternating chirality of pyrrolidine units, Frontiers in Chemisrty, 6(91), 1-12. DOI: 10.3389/fchem.2018.00091.
Область экспертизы: 

Структура и динамика биомолекул, спектроскопия ядерного магнитного резонанса, белок-лигандные взаимодействия, молекулярная фармакология, ЯМР-скрининг биологически активных соединений.

Дополнительные сведения: 

Редактор по направлению «молекулярная фармакология» журнала «Central European Journal of Medicine» (Springer)

Curriculum Vitae: 
Иконка PDF cv_vp_18.pdf